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KDM2A 抗体 (Middle Region)

This anti-KDM2A antibody is a 兔 多克隆 antibody detecting KDM2A in WB. Suitable for 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, Pig 和 豚鼠.
产品编号 ABIN2787493
发货至: 中国

Quick Overview for KDM2A 抗体 (Middle Region) (ABIN2787493)

抗原

See all KDM2A 抗体
KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

适用

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人, 小鼠, 大鼠, 犬, 马, 兔, Cow, Pig, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This KDM2A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    LTPPADKPGQ DNRSKLRNMT DFRLAGLDIT DATLRLIIRH MPLLSRLDLS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against KDM2A. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of Human KDM2A
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

    别名

    KDM2A

    背景

    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3.
    Alias Symbols: CXXC8, FBL11, FBL7, FBXL11, JHDM1A, LILINA
    Protein Interaction Partner: RB1, E2F1, EED, SKP1, MPG, ZNF512B, UBE2G2, SMAD7, SMAD3, HIST3H3, HIST2H3C, KIAA0368, ELAVL1, UBC, BCL6, FOS, RELA,
    Protein Size: 620

    分子量

    68 kDa

    基因ID

    22992

    NCBI登录号

    NM_012308, NP_036440

    途径

    Warburg Effect
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