PKM2 抗体 (Middle Region)
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北京 101111
Quick Overview for PKM2 抗体 (Middle Region) (ABIN2787394)
抗原
See all PKM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- PKM2 Antibody - middle region
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序列
- HLQLFEELRR LAPITSDPTE ATAVGAVEAS FKCCSGAIIV LTKSGRSAHQ
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 77%, Yeast: 85%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against PKM2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PKM2
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anti-Pyruvate Kinase M2 (PKM2) (AA 294-470) antibody
PKM2 适用: 人 WB, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505), (C-Term) antibodyPKM2 适用: 人, 小鼠, 大鼠, 猴 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB3697 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 141-248) antibodyPKM2 适用: 人 WB, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (pTyr105) antibodyPKM2 适用: 人 WB, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibodyPKM2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18405 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (Internal Region) antibodyPKM2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 255-350) antibodyPKM2 适用: 小鼠 WB, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibodyPKM2 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505) antibodyPKM2 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 116-145), (N-Term) antibodyPKM2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB15338 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57789-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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别名
- PKM2
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背景
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Background Information: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Gene Name: Pyruvate kinase, muscle
Alternative Symbols: PK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1, HEL-S-30
Protein Name: Pyruvate kinase isozymes M1/M2
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分子量
- 58kDa
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基因ID
- 5315
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NCBI登录号
- NP_002645
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UniProt
- P11980
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途径
- Warburg Effect
抗原
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