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PKM2 抗体 (N-Term)

PKM2 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787393
发货至: 中国
  • 抗原 See all PKM2 抗体
    PKM2 (Pyruvate Kinase M2 (PKM2))
    抗原表位
    • 16
    • 16
    • 15
    • 12
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 147
    • 100
    • 87
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马
    宿主
    • 124
    • 22
    • 5
    • 1
    克隆类型
    • 130
    • 22
    多克隆
    标记
    • 60
    • 13
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PKM2 antibody is un-conjugated
    应用范围
    • 88
    • 36
    • 27
    • 27
    • 24
    • 19
    • 17
    • 15
    • 10
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MSKPHSEAGT AFIQTQQLHA AMADTFLEHM CRLDIDSPPI TARNTGIICT
    预测反应
    Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against PKM2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PKM2
    Top Product
    Discover our top product PKM2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 531 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PKM2 (Pyruvate Kinase M2 (PKM2))
    别名
    PKM2 (PKM2 产品)
    别名
    CTHBP antibody, OIP3 antibody, PK3 antibody, PKM2 antibody, TCB antibody, THBP1 antibody, AA414905 antibody, AL024370 antibody, AL024424 antibody, Pk-2 antibody, Pk-3 antibody, Pk3 antibody, Pkm2 antibody, PKM12 antibody, PKM antibody, pyruvate kinase M1/2 antibody, pyruvate kinase, muscle antibody, PKM antibody, Pkm antibody
    背景
    This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
    Alias Symbols: CTHBP, MGC3932, OIP3, PK3, PKM, TCB, THBP1, PKM2
    Protein Interaction Partner: LNX1, NXT2, HUWE1, ISG15, UBC, POLE2, FUS, SUMO2, SUMO3, STAU1, MDM2, SUZ12, EZH2, IPO11, TWF2, PDLIM5, NPLOC4, PLIN3, UBA2, EIF4A3, ANP32A, SRP14, RAD23B, PPP1CA, PIN1, CTPS1, CBS, CAPZA2, ACAT2, NLK, FBXO6, YWHAQ, RAF1, IGSF8, HDAC6, MAPK7, NPM1, CDK2,
    Protein Size: 531
    分子量
    58 kDa
    基因ID
    5315
    NCBI登录号
    NM_002654, NP_002645
    UniProt
    P14618
    途径
    Warburg Effect
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