RAD1 抗体 (Middle Region)
Quick Overview for RAD1 抗体 (Middle Region) (ABIN2787356)
抗原
See all RAD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- ITMSPDKPYF RLSTFGNAGS SHLDYPKDSD LMEAFHCNQT QVNRYKISLL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against RAD1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RAD1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 282 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))
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别名
- RAD1
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背景
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This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.
Alias Symbols: HRAD1, REC1
Protein Interaction Partner: ATRX, FEN1, UBC, MSH3, MSH2, MSH6, COPS5, HUS1, ATR, MAP1LC3B, HUS1B, RAD9B, RAD17, POLB, DNAJC7, PARK2, RPA2, RPA1, RAD9A,
Protein Size: 282 -
分子量
- 32 kDa
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基因ID
- 5810
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NCBI登录号
- NM_002853, NP_002844
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UniProt
- O60671
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途径
- M Phase
抗原
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