OPA1 抗体 (N-Term)
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- 抗原 See all OPA1 抗体
- OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OPA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SPEETAFRAT DRGSESDKHF RKVSDKEKID QLQEELLHTQ LKYQRILERL
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against OPA1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product OPA1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 924 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))
- 别名
- OPA1 (OPA1 产品)
- 背景
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This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ12460, KIAA0567, MGM1, NPG, NTG, largeG
Protein Interaction Partner: UBC, PARK2, MYC, HSP90AA5P, NIT2, HTRA2, NPTX1, NDUFS8, NDUFS1, NDUFA9, ILF3, HADHB, ECH1, DNASE2, APP, SMAD3, SMAD2, CAND1, CUL3, ELAVL1, MME,
Protein Size: 924 - 分子量
- 102 kDa
- 基因ID
- 4976
- NCBI登录号
- NM_130831, NP_570844
- UniProt
- E5KLK2
- 途径
- Tube Formation
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