MFN1 抗体 (Middle Region)
Quick Overview for MFN1 抗体 (Middle Region) (ABIN2787347)
抗原
See all MFN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- QVDITQKQLE EEIARLPKEI DQLEKIQNNS KLLRNKAVQL ENELENFTKQ
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预测反应
- Cow: 100%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against MFN1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MFN1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 741 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 9, pp. 1518-35, (2013) (PubMed).
: "Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes." in: Molecular and cellular biology, Vol. 31, Issue 6, pp. 1309-28, (2011) (PubMed).
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Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 9, pp. 1518-35, (2013) (PubMed).
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- MFN1 (Mitofusin 1 (MFN1))
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别名
- MFN1
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背景
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The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.
Alias Symbols: DKFZp762F247, FLJ20693, MGC41806, hfzo1, hfzo2
Protein Interaction Partner: PARK2, MARCH5, UBC, TER94, MAVS, CCNB1, ILF2, BAK1,
Protein Size: 741 -
分子量
- 84 kDa
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基因ID
- 55669
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NCBI登录号
- NM_033540, NP_284941
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UniProt
- Q8R4Z9
抗原
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