NECAB3 抗体 (Middle Region)
Quick Overview for NECAB3 抗体 (Middle Region) (ABIN2787332)
抗原
See all NECAB3 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- Middle Region
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                                            序列
- ESVEAQSRLC GSRRAGRRAL RSVSRSSTWS PGSSDTGRSS EAEMQWRLQV
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                                            预测反应
- Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%
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                                            产品特性
- This is a rabbit polyclonal antibody against NECAB3. It was validated on Western Blot using a cell lysate as a positive control.
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                                            纯化方法
- Affinity Purified
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                                            免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NECAB3
 
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                                            应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            说明
- 
                        Antigen size: 396 AA 
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- Lot specific
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                                            缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freeze-thaw cycles.
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                                            储存条件
- -20 °C
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                                            储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
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                                            别名
- NECAB3
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                                            背景
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                        The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
 Alias Symbols: APBA2BP, EFCBP3, NIP1, STIP3, SYTIP2, XB51, dJ63M2.4, dJ63M2.5
 Protein Interaction Partner: UBC, APP, MYC, IKBKG, APBA2,
 Protein Size: 396
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                                            分子量
- 44 kDa
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                                            基因ID
- 63941
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                                            NCBI登录号
- NM_031232, NP_112509
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                                            UniProt
- Q96P71
 抗原
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