NECAB3 抗体 (N-Term)
Quick Overview for NECAB3 抗体 (N-Term) (ABIN2787331)
抗原
See all NECAB3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- MACAGLLTVC LLRPPAPQPQ PQTPRHPQLA PDPGPAGHTL FQDVFRRADK
-
预测反应
- Cow: 79%, Dog: 90%, Horse: 77%, Human: 100%, Mouse: 83%, Pig: 90%, Rat: 90%, Yeast: 100%
-
产品特性
- This is a rabbit polyclonal antibody against NECAB3. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NECAB3
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 396 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
-
别名
- NECAB3
-
背景
-
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: APBA2BP, EFCBP3, NIP1, STIP3, SYTIP2, XB51, dJ63M2.4, dJ63M2.5
Protein Interaction Partner: UBC, APP, MYC, IKBKG, APBA2,
Protein Size: 396 -
分子量
- 44 kDa
-
基因ID
- 63941
-
NCBI登录号
- NM_031232, NP_112509
-
UniProt
- Q96P71
抗原
-