CHMP1B 抗体 (N-Term)
Quick Overview for CHMP1B 抗体 (N-Term) (ABIN2787213)
抗原
See all CHMP1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- KIKKAIQKGN MEVARIHAEN AIRQKNQAVN FLRMSARVDA VAARVQTAVT
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预测反应
- Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against CHMP1B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CHMP1B
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 199 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))
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别名
- CHMP1B
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背景
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CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Alias Symbols: C10orf2, C18-ORF2, C18orf2, CHMP1.5, Vps46-2, Vps46B, hVps46-2
Protein Interaction Partner: STAMBP, UBC, ATP6V1B1, CHMP4B, KNSTRN, CHMP1B, CHMP5, VPS4A, CNOT10, SNRNP200, SUCLG1, RAB11A, RASSF7, SSRP1, CHMP1A, USP54, USP8, SPAST, ELAVL1, IST1, VPS4B,
Protein Size: 199 -
分子量
- 22 kDa
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基因ID
- 57132
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NCBI登录号
- NM_020412, NP_065145
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UniProt
- Q7LBR1
抗原
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