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CHMP1B 抗体 (AA 1-199)

CHMP1B 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7147518
发货至: 中国
  • 抗原 See all CHMP1B 抗体
    CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))
    抗原表位
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-199
    适用
    • 24
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 23
    • 1
    克隆类型
    • 24
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHMP1B antibody is un-conjugated
    应用范围
    • 23
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Charged multivesicular body protein 1b protein (1-199AA)
    亚型
    IgG
    Top Product
    Discover our top product CHMP1B Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))
    别名
    CHMP1B (CHMP1B 产品)
    别名
    C10orf2 antibody, C18-ORF2 antibody, C18orf2 antibody, CHMP1.5 antibody, Vps46-2 antibody, Vps46B antibody, hVps46-2 antibody, 2810405I11Rik antibody, Chmp1b1 antibody, Chmp1.5 antibody, fb10c03 antibody, wu:fb10c03 antibody, zgc:56134 antibody, chromatin modifying protein 1b antibody, hypothetical protein antibody, charged multivesicular body protein 1B antibody, chromatin modifying protein 1B antibody, LOC692931 antibody, PGTG_18215 antibody, CHMP1B antibody, Chmp1b antibody, chmp1b antibody
    背景

    Background: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in HIV-1 p6- and p9-dependent virus release.

    Aliases: CHMP1B antibody, C18orf2Charged multivesicular body protein 1b antibody, CHMP1.5 antibody, Chromatin-modifying protein 1b antibody, CHMP1b antibody, Vacuolar protein sorting-associated protein 46-2 antibody, Vps46-2 antibody, hVps46-2 antibody

    UniProt
    Q7LBR1
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