TDP1 抗体 (C-Term)
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Quick Overview for TDP1 抗体 (C-Term) (ABIN2787113)
抗原
See all TDP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GRPPGKSAVP LHLIYPSVEN VRTSLEGYPA GGSLPYSIQT AEKQRWLHSY
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against Tdp1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of mouse TDP1
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anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibody
TDP1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-260) antibodyTDP1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-298) antibodyTDP1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal AT1F2 unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) antibodyTDP1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-140) antibodyTDP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibodyTDP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibodyTDP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A10-G2 unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-298) antibodyTDP1 适用: 人 WB, ELISA, IF, ICC, FACS 宿主: 小鼠 Monoclonal AT1F2 unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Internal Region) antibodyVerified TDP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 350-399) antibodyTDP1 适用: 人, 小鼠, 马, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
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别名
- Tdp1
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背景
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The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.
Protein Size: 609 -
分子量
- 66 kDa
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基因ID
- 55775
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NCBI登录号
- NM_001008744, NP_001008744
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UniProt
- Q9NUW8
抗原
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