TDP1 抗体 (Middle Region)
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北京 101111
Quick Overview for TDP1 抗体 (Middle Region) (ABIN2787112)
抗原
See all TDP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Tdp1 Antibody - middle region
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序列
- ETNVYLIGST PGRFQGSHRD NWGHFRLRKL LQAHAPSTPK GECWPIVGQF
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预测反应
- Cow: 92%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against Tdp1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibody
TDP1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-298) antibodyTDP1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal AT1F2 unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-260) antibodyTDP1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) antibodyTDP1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-50) antibodyTDP1 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-140) antibodyTDP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (C-Term) antibodyTDP1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibodyTDP1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibodyTDP1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2A10-G2 unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Internal Region) antibodyVerified TDP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57199-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
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别名
- Tdp1
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背景
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Background Information: Tdp1 is a DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. It catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. It hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. It acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. It has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. It has no exonuclease activity towards DNA or RNA with a 3'phosphate.
Gene Name: Tyrosyl-DNA phosphodiesterase 1
Alternative Symbols: SC, SCAN1, Gm40556, MLZ-501, AI838772, AW493413, 2810481F14Rik, 4921509N21Rik, E430034L06Rik
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分子量
- 64kDa
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基因ID
- 104884
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NCBI登录号
- NP_082630
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UniProt
- Q8BJ37
抗原
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