TDP1 抗体 (Middle Region)
Quick Overview for TDP1 抗体 (Middle Region) (ABIN2787112)
抗原
See all TDP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- ETNVYLIGST PGRFQGSHRD NWGHFRLRKL LQAHAPSTPK GECWPIVGQF
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预测反应
- Cow: 92%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against Tdp1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibody
TDP1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-260) antibodyTDP1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) antibodyTDP1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibodyTDP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibodyTDP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A10-G2 unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-140) antibodyTDP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Internal Region) antibodyVerified TDP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 350-399) antibodyTDP1 适用: 人, 小鼠, 马, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-298) antibodyTDP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT1F2 unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 4-215) antibodyTDP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 579 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
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别名
- Tdp1
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背景
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Tdp1 is a DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. It catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. It hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. It acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. It has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. It has no exonuclease activity towards DNA or RNA with a 3'phosphate.
Alias Symbols: 2810481F14Rik, 4921509N21Rik, AI838772, AW493413, E430034L06Rik, SCAN1, MLZ-501
Protein Size: 579 -
分子量
- 64 kDa
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基因ID
- 104884
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NCBI登录号
- NM_028354, NP_082630
抗原
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