TBC1D7 抗体 (C-Term)
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- 抗原 See all TBC1D7 抗体
- TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 犬, 山羊, 兔, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TBC1D7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ISRCFVKQLN NKYRDALPQL PKAFEQYLNL EDSRLLSHLK TCSAVSKLPY
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against Tbc1d7. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Tbc1d7
- Top Product
- Discover our top product TBC1D7 Primary Antibody
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anti-TBC1 Domain Family, Member 7 (TBC1D7) (AA 1-293) antibody
TBC1D7 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 7 (TBC1D7) (AA 1-293) antibodyTBC1D7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 7 (TBC1D7) antibodyTBC1D7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 7 (TBC1D7) (AA 154-203) antibodyTBC1D7 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 293 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
- 别名
- Tbc1d7 (TBC1D7 产品)
- 别名
- PIG51 antibody, TBC7 antibody, dJ257A7.3 antibody, 2610009C09Rik antibody, TBC1 domain family member 7 antibody, TBC1 domain family, member 7 antibody, TBC1D7 antibody, Tbc1d7 antibody
- 背景
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Tbc1d7 is a component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.
Alias Symbols: 2610009C09Rik
Protein Interaction Partner: Ywhae,
Protein Size: 293 - 分子量
- 32 kDa
- 基因ID
- 67046
- NCBI登录号
- NM_025935, NP_080211
- UniProt
- Q9D0K0
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