TBC1D7 抗体 (C-Term)
Quick Overview for TBC1D7 抗体 (C-Term) (ABIN2786978)
抗原
See all TBC1D7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- ISRCFVKQLN NKYRDALPQL PKAFEQYLNL EDSRLLSHLK TCSAVSKLPY
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against Tbc1d7. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Tbc1d7
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anti-TBC1 Domain Family, Member 7 (TBC1D7) (AA 1-293) antibody
TBC1D7 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 7 (TBC1D7) (AA 1-293) antibodyTBC1D7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 7 (TBC1D7) (AA 154-203) antibodyTBC1D7 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 7 (TBC1D7) antibodyTBC1D7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 293 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
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别名
- Tbc1d7
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背景
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Tbc1d7 is a component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.
Alias Symbols: 2610009C09Rik
Protein Interaction Partner: Ywhae,
Protein Size: 293 -
分子量
- 32 kDa
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基因ID
- 67046
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NCBI登录号
- NM_025935, NP_080211
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UniProt
- Q9D0K0
抗原
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