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SCP2 抗体 (Middle Region)

This anti-SCP2 antibody is a 兔 多克隆 antibody detecting SCP2 in WB. Suitable for 人, 小鼠, 大鼠, 豚鼠, 马 和 斑马鱼.
产品编号 ABIN2786761
发货至: 中国

Quick Overview for SCP2 抗体 (Middle Region) (ABIN2786761)

抗原

See all SCP2 抗体
SCP2 (Sterol Carrier Protein 2 (SCP2))

适用

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人, 小鼠, 大鼠, 豚鼠, 马, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This SCP2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    NHKHSVNNPY SQFQDEYSLD EVMASKEVFD FLTILQCCPT SDGAAAAILA

    预测反应

    Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against SCP2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human SCP2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 322 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SCP2 (Sterol Carrier Protein 2 (SCP2))

    别名

    SCP2

    背景

    SCP2 protein is thought to be an intracellular lipid transfer protein. SCP2 is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis.This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined.
    Alias Symbols: DKFZp686C12188, DKFZp686D11188, NLTP, NSL-TP, SCPX, SCP-2, SCP-X, SCP-CHI
    Protein Interaction Partner: TRIP13, UBC, PEX5, MPLKIP, MRRF, SUGP1, MRPS28, TBL2, SRRM2, RAB31, SEPT9, TIMM44, ECI2, SCO2, AGPS, STX7, UBL4A, VDAC3, VDAC2, RRBP1, RBMS1, NDUFA7, IDH3G, HSD17B4, ACAA1, RAB8A, ELAVL1, CACNA1A, ACAA2, EHHADH, CAV1, ACOX1, PITPNA,
    Protein Size: 322

    分子量

    35 kDa

    基因ID

    6342

    NCBI登录号

    NM_001007098, NP_001007099

    UniProt

    Q6NXF4

    途径

    C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process
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