SCP2 抗体 (Middle Region)
Quick Overview for SCP2 抗体 (Middle Region) (ABIN2786761)
抗原
See all SCP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- NHKHSVNNPY SQFQDEYSLD EVMASKEVFD FLTILQCCPT SDGAAAAILA
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预测反应
- Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against SCP2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SCP2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 322 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SCP2 (Sterol Carrier Protein 2 (SCP2))
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别名
- SCP2
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背景
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SCP2 protein is thought to be an intracellular lipid transfer protein. SCP2 is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis.This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined.
Alias Symbols: DKFZp686C12188, DKFZp686D11188, NLTP, NSL-TP, SCPX, SCP-2, SCP-X, SCP-CHI
Protein Interaction Partner: TRIP13, UBC, PEX5, MPLKIP, MRRF, SUGP1, MRPS28, TBL2, SRRM2, RAB31, SEPT9, TIMM44, ECI2, SCO2, AGPS, STX7, UBL4A, VDAC3, VDAC2, RRBP1, RBMS1, NDUFA7, IDH3G, HSD17B4, ACAA1, RAB8A, ELAVL1, CACNA1A, ACAA2, EHHADH, CAV1, ACOX1, PITPNA,
Protein Size: 322 -
分子量
- 35 kDa
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基因ID
- 6342
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NCBI登录号
- NM_001007098, NP_001007099
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UniProt
- Q6NXF4
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途径
- C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process
抗原
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