PKC iota 抗体 (Middle Region)
Quick Overview for PKC iota 抗体 (Middle Region) (ABIN2786697)
抗原
See all PKC iota (PRKCI) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- TVIPYNPSSH ESLDQVGEEK EAMNTRESGK ASSSLGLQDF DLLRVIGRGS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PRKCI. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PRKCI
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anti-Protein Kinase C, iota (PRKCI) (AA 375-596) antibody
PRKCI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, iota (PRKCI) (AA 1-587) antibodyPRKCI 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-Protein Kinase C, iota (PRKCI) (AA 21-214) antibodyPRKCI 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, iota (PRKCI) (AA 1-100) antibodyPRKCI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-Protein Kinase C, iota (PRKCI) (AA 176-207), (N-Term) antibodyPRKCI 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01026 unconjugated
anti-Protein Kinase C, iota (PRKCI) (Internal Region) antibodyPRKCI 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, iota (PRKCI) (AA 215-264) antibodyPRKCI 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 596 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
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别名
- PRKCI
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背景
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This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.
Alias Symbols: DXS1179E, MGC26534, PKCI, nPKC-iota
Protein Interaction Partner: PARD6B, PARD6A, UBC, AMOT, SQSTM1, CRX, NPM1, IKBKG, YWHAE, IL1RAP, HSP90AA1, GAB1, CASP8, PARD3, APP, UBD, MAP2K5, MARK2, ARHGAP17, TJP1, ELAVL1, CDK7, MBP, TSC22D1, TTR, FABP4, PARD6G, MARK4, CDC37, RAPGEF2, PNMA1, NIPSNAP1, YWHAZ, YWHAH, MYO10, LLGL1,
Protein Size: 596 -
分子量
- 68 kDa
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基因ID
- 5584
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NCBI登录号
- NM_002740, NP_002731
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UniProt
- P41743
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途径
- Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
抗原
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