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PRELP 抗体 (Middle Region)

This anti-PRELP antibody is a 兔 多克隆 antibody detecting PRELP in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig 和 兔.
产品编号 ABIN2786687
发货至: 中国

Quick Overview for PRELP 抗体 (Middle Region) (ABIN2786687)

抗原

See all PRELP 抗体
PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔

宿主

  • 21
  • 4
  • 1

克隆类型

  • 24
  • 2
多克隆

标记

  • 19
  • 2
  • 2
  • 1
  • 1
  • 1
This PRELP antibody is un-conjugated

应用范围

  • 22
  • 12
  • 11
  • 8
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    SNKIETIPNG YFKSFPNLAF IRLNYNKLTD RGLPKNSFNI SNLLVLHLSH

    预测反应

    Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against PRELP. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human PRELP
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 382 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

    别名

    PRELP

    背景

    PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.
    Alias Symbols: MGC45323, MST161, MSTP161, SLRR2A
    Protein Interaction Partner: Dlg4, HSPG2, FBLN2, FN1, NID1, COL1A1, COL2A1, NID2,
    Protein Size: 382

    分子量

    42 kDa

    基因ID

    5549

    NCBI登录号

    NM_002725, NP_002716

    UniProt

    P51888

    途径

    Glycosaminoglycan Metabolic Process
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