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ATP6V1B2 抗体 (N-Term)

ATP6V1B2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786642
发货至: 中国
  • 抗原 See all ATP6V1B2 抗体
    ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))
    抗原表位
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 19
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 斑马鱼
    宿主
    • 13
    • 6
    克隆类型
    • 15
    • 4
    多克隆
    标记
    • 19
    This ATP6V1B2 antibody is un-conjugated
    应用范围
    • 18
    • 9
    • 5
    • 2
    • 1
    Western Blotting (WB)
    序列
    VSRNYLSQPR LTYKTVSGVN GPLVILDHVK FPRYAEIVHL TLPDGTKRSG
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against ATP6V1B2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V1B2
    Top Product
    Discover our top product ATP6V1B2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 511 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))
    别名
    ATP6V1B2 (ATP6V1B2 产品)
    背景
    ATP6V1B2 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. ATP6V1B2 is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2
    Protein Interaction Partner: TCF4, UBC, PBDC1, GMPPB, GANAB, SWAP70, MSH2, JUP, MSH6, XRCC6, CRMP1, HYOU1, SEC24C, CUL2, SUPT5H, SSRP1, PDE3A, CSDE1, PAN2, FN1, SRXN1, YIF1B, UNK, ZFYVE19, TUBA1C, INTS2, TRMT1, ABCF3, ATP6V1H, CCT8, SSSCA1, TUBB4B, UBA2, USP34, ATP6V1F, ZBED1, ZPR1,
    Protein Size: 511
    分子量
    56 kDa
    基因ID
    526
    NCBI登录号
    NM_001693, NP_001684
    UniProt
    P21281
    途径
    Transition Metal Ion Homeostasis, Proton Transport
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