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PPOX 抗体 (N-Term)

This anti-PPOX antibody is a 兔 多克隆 antibody detecting PPOX in WB. Suitable for 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, 犬 和 Pig. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2786509
发货至: 中国

Quick Overview for PPOX 抗体 (N-Term) (ABIN2786509)

抗原

See all PPOX 抗体
PPOX (Protoporphyrinogen Oxidase (PPOX))

适用

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人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, 犬, Pig

宿主

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克隆类型

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多克隆

标记

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This PPOX antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    SSERLGGWIR SVRGPNGAIF ELGPRGIRPA GALGARTLLL VSELGLDSEV

    预测反应

    Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against PPOX. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PPOX
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 477 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • de Vooght, van Wijk, van Solinge: "GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX." in: Gene, Vol. 409, Issue 1-2, pp. 83-91, (2008) (PubMed).

  • 抗原

    PPOX (Protoporphyrinogen Oxidase (PPOX))

    别名

    PPOX

    背景

    PPOX catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX..This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
    Alias Symbols: MGC8485, PPO, V290M, VP
    Protein Interaction Partner: HNRNPD, UBC, COPS5, HAP1, PPOX, IMMT,
    Protein Size: 477

    分子量

    51 kDa

    基因ID

    5498

    NCBI登录号

    NM_000309, NP_000300

    UniProt

    P50336

    途径

    Synaptic Membrane, Feeding Behaviour
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