RHOC 抗体 (N-Term)
(1 reference)Quick Overview for RHOC 抗体 (N-Term) (ABIN2786344)
抗原
See all RHOC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VPTVFENYIA DIEVDGKQVE LALWDTAGQE DYDRLRPLSY PDTDVILMCF
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against RHOC. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RHOC
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anti-Ras Homolog Gene Family, Member C (RHOC) (AA 1-193) antibody
RHOC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Ras Homolog Gene Family, Member C (RHOC) (AA 1-193) antibodyRHOC 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Ras Homolog Gene Family, Member C (RHOC) antibodyRHOC 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member C (RHOC) (AA 101-193) antibodyRHOC 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IHC (fro), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member C (RHOC) (C-Term) antibodyRHOC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member C (RHOC) (AA 91-190) antibodyRHOC 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member C (RHOC) (AA 1-190) antibodyRHOC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member C (RHOC) (AA 35-84) antibodyRHOC 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼, Drosophila melanogaster, 小鸡, Insect, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member C (RHOC) (N-Term) antibodyRHOC 适用: 人, 小鼠, 大鼠, 犬, Drosophila melanogaster, C. elegans WB 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member C (RHOC) antibodyRHOC 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 193 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets." in: BMC cancer, Vol. 8, pp. 19, (2008) (PubMed).
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: "Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets." in: BMC cancer, Vol. 8, pp. 19, (2008) (PubMed).
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- RHOC (Ras Homolog Gene Family, Member C (RHOC))
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别名
- RHOC
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背景
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RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: ARH9, ARHC, H9, MGC1448, MGC61427, RHOH9
Protein Interaction Partner: FAM65B, UBC, env, ATF2, PPP3CA, CDK2, LNX1, CAV1, CIT, ARHGAP1, RTKN, DIAPH1, ROCK1, VHL, ARHGDIA,
Protein Size: 193 -
分子量
- 22 kDa
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基因ID
- 389
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NCBI登录号
- NM_175744, NP_786886
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UniProt
- P08134
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途径
- WNT signaling, Cell-Cell Junction Organization
抗原
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