NSMCE2 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for NSMCE2 抗体 (Middle Region) (ABIN2786320)
抗原
See all NSMCE2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- KFLALQSKNS DADFQNNEKF VQFKQQLKEL KKQCGLQADR EADGTEGVDE
-
预测反应
- Cow: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 100%
-
产品特性
- This is a rabbit polyclonal antibody against NSMCE2. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NSMCE2
-
-
anti-E3 SUMO-Protein Ligase NSE2 (NSMCE2) (AA 1-247) antibody
NSMCE2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-E3 SUMO-Protein Ligase NSE2 (NSMCE2) (AA 1-247) antibodyNSMCE2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E3 SUMO-Protein Ligase NSE2 (NSMCE2) (AA 107-156) antibodyNSMCE2 适用: 人, 兔, 马, Cow, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-E3 SUMO-Protein Ligase NSE2 (NSMCE2) (N-Term) antibodyNSMCE2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 247 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
-
别名
- NSMCE2
-
背景
-
NSMCE2 is the E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. NSMCE2 acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.
Alias Symbols: C8orf36, FLJ32440, MMS21, NSE2
Protein Interaction Partner: TXLNA, PAN2, UBC, NSMCE1, SMC6, PDS5A, SMC5, WAPAL, PDS5B, STAG2, SMC3, SMC1A, SUMO1, TSNAX, RAD21, ETV1, SUMO2,
Protein Size: 247 -
分子量
- 28 kDa
-
基因ID
- 286053
-
NCBI登录号
- NM_173685, NP_775956
-
UniProt
- Q96MF7
抗原
-
