SKA1 抗体 (Middle Region)
Quick Overview for SKA1 抗体 (Middle Region) (ABIN2786219)
抗原
See all SKA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LLNKFELEIQ YQEQTNSSLK ELCESLREEC EDVEHLKEHV PPHLPQVTAT
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预测反应
- Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against Ska1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) (C-Term) antibody
SKA1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) (AA 61-134) antibodySKA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) (AA 51-100) antibodySKA1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 254 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
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别名
- Ska1
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背景
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Ska1 is a Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. It is required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules.
Alias Symbols: 2810433K01Rik, AV117428
Protein Size: 254 -
分子量
- 28 kDa
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基因ID
- 66468
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NCBI登录号
- NM_025581, NP_079857
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UniProt
- Q9CPV1
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途径
- M Phase
抗原
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