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ALKBH3 抗体 (Middle Region)

This anti-ALKBH3 antibody is a 兔 多克隆 antibody detecting ALKBH3 in WB. Suitable for 人, 小鼠, 大鼠, 马, 兔, Cow, 犬, 豚鼠 和 Pig. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2786204
发货至: 中国

Quick Overview for ALKBH3 抗体 (Middle Region) (ABIN2786204)

抗原

See all ALKBH3 抗体
ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))

适用

人, 小鼠, 大鼠, 马, 兔, Cow, 犬, 豚鼠, Pig

宿主

  • 29
  • 2

克隆类型

  • 29
  • 2
多克隆

标记

  • 18
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
This ALKBH3 antibody is un-conjugated

应用范围

  • 20
  • 18
  • 9
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    EMRKKPPPEE NGDYTYVERV KIPLDHGTLL IMEGATQADW QHRVPKEYHS

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against ALKBH3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ALKBH3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 286 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sundheim, Vågbø, Bjørås, Sousa, Talstad, Aas, Drabløs, Krokan, Tainer, Slupphaug: "Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage." in: The EMBO journal, Vol. 25, Issue 14, pp. 3389-97, (2006) (PubMed).

  • 抗原

    ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))

    别名

    ALKBH3

    背景

    The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine.The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM]. Sequence Note: removed 1 base from the 5' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1519 AB042029.1 2-1520
    Alias Symbols: ABH3, DEPC-1, DEPC1, MGC118790, MGC118792, MGC118793, PCA1
    Protein Interaction Partner: AK8, LNX1, GLRX3, IKZF1, GOLGA2, SRPK2, SRPK1,
    Protein Size: 286

    分子量

    33 kDa

    基因ID

    221120

    NCBI登录号

    NM_139178, NP_631917

    UniProt

    Q96Q83

    途径

    DNA Damage Repair
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