ALKBH3 抗体 (Middle Region)
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北京 101111
Quick Overview for ALKBH3 抗体 (Middle Region) (ABIN2786204)
抗原
See all ALKBH3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- EMRKKPPPEE NGDYTYVERV KIPLDHGTLL IMEGATQADW QHRVPKEYHS
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against ALKBH3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ALKBH3
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anti-AlkB, Alkylation Repair Homolog 3 (ALKBH3) (AA 1-170) antibody
ALKBH3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 3 (ALKBH3) (AA 1-139) antibodyALKBH3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A5-4F5 unconjugated
anti-AlkB, Alkylation Repair Homolog 3 (ALKBH3) (Internal Region) antibodyALKBH3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 3 (ALKBH3) (AA 216-265) antibodyALKBH3 适用: 人, 小鼠, 大鼠, 马, 兔, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 3 (ALKBH3) (AA 1-286) antibodyALKBH3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 3 (ALKBH3) (AA 1-286) antibodyALKBH3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 3 (ALKBH3) (AA 242-269), (C-Term) antibodyALKBH3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB22074 unconjugated
anti-AlkB, Alkylation Repair Homolog 3 (ALKBH3) (AA 1-286) antibody (APC)ALKBH3 适用: 人 IHC, IF, FACS, ICC 宿主: 兔 Polyclonal APC
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 286 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage." in: The EMBO journal, Vol. 25, Issue 14, pp. 3389-97, (2006) (PubMed).
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: "Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage." in: The EMBO journal, Vol. 25, Issue 14, pp. 3389-97, (2006) (PubMed).
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- ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
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别名
- ALKBH3
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背景
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The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine.The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM]. Sequence Note: removed 1 base from the 5' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1519 AB042029.1 2-1520
Alias Symbols: ABH3, DEPC-1, DEPC1, MGC118790, MGC118792, MGC118793, PCA1
Protein Interaction Partner: AK8, LNX1, GLRX3, IKZF1, GOLGA2, SRPK2, SRPK1,
Protein Size: 286 -
分子量
- 33 kDa
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基因ID
- 221120
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NCBI登录号
- NM_139178, NP_631917
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UniProt
- Q96Q83
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途径
- DNA Damage Repair
抗原
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