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DKK2 抗体 (Middle Region)

This anti-DKK2 antibody is a 兔 多克隆 antibody detecting DKK2 in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 和 兔.
产品编号 ABIN2786024
发货至: 中国
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Quick Overview for DKK2 抗体 (Middle Region) (ABIN2786024)

抗原

See all DKK2 抗体
DKK2 (Dickkopf 2 Homolog (DKK2))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔

宿主

  • 46
  • 5
  • 1

克隆类型

  • 47
  • 5
多克隆

标记

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This DKK2 antibody is un-conjugated

应用范围

  • 38
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Western Blotting (WB)
  • 抗原表位

    • 8
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    Middle Region

    序列

    NGICIPVTES ILTPHIPALD GTRHRDRNHG HYSNHDLGWQ NLGRPHSKMP

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against Dkk2. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide corresponding to a region of Mouse
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 259 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    DKK2 (Dickkopf 2 Homolog (DKK2))

    别名

    Dkk2

    背景

    Dkk2 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer's disease.
    Alias Symbols: -
    Protein Size: 259

    分子量

    28 kDa

    基因ID

    56811

    NCBI登录号

    NM_020265, NP_064661

    UniProt

    Q9QYZ8

    途径

    WNT signaling
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