TBK1 抗体 (N-Term)
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- 抗原 See all TBK1 抗体
- TBK1 (TANK-Binding Kinase 1 (TBK1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TBK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EEETTTRHKV LIMEFCPCGS LYTVLEEPSN AYGLPESEFL IVLRDVVGGM
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against TBK1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TBK1
- Top Product
- Discover our top product TBK1 Primary Antibody
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anti-TANK-Binding Kinase 1 (TBK1) (AA 440-729) antibody
TBK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) antibodyTBK1 适用: 人 WB, IP, IF 宿主: 兔 Monoclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (pSer172) antibodyTBK1 适用: 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 9-310) antibodyTBK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 150-181) antibodyTBK1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB16573 unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 364-585) antibodyTBK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (C-Term) antibodyTBK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 644-661) antibodyTBK1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 74-123) antibodyTBK1 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, Pig, 兔, 马, 豚鼠, 斑马鱼, Hamster, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (Internal Region) antibodyTBK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 729 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TBK1 (TANK-Binding Kinase 1 (TBK1))
- 别名
- TBK1 (TBK1 产品)
- 别名
- nak antibody, t2k antibody, TBK1 antibody, wu:fk70c05 antibody, zgc:136548 antibody, NAK antibody, T2K antibody, 1200008B05Rik antibody, AI462036 antibody, AW048562 antibody, TANK binding kinase 1 L homeolog antibody, TANK binding kinase 1 antibody, TANK-binding kinase 1 antibody, tbk1.L antibody, TBK1 antibody, tbk1 antibody, Tbk1 antibody
- 背景
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The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TBK1 is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ11330, NAK, T2K
Protein Interaction Partner: UBC, Trim11, AZI2, TBK1, TANK, TBKBP1, EGFR, TMEM173, TRAF3, EXOC2, MIB1, LATS2, ANKRD28, DDX58, SYK, TRAF3IP2, TOMM70A, STX11, PROS1, IRF3, HSP90AA1, XIAP, RNF11, YWHAE, APP, NFKBIA, IKBKG, TRAF2, MAVS, OPTN, SRC, RELA, TICAM1, MBP, IRF7, IKBKE, HERC2, T
Protein Size: 729 - 分子量
- 84 kDa
- 基因ID
- 29110
- NCBI登录号
- NM_013254, NP_037386
- UniProt
- Q9UHD2
- 途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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