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INPP5B 抗体 (Middle Region)

This anti-INPP5B antibody is a 兔 多克隆 antibody detecting INPP5B in WB. Suitable for 人, 小鼠, 大鼠, 犬, 兔, 豚鼠 和 马. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2785875
发货至: 中国

Quick Overview for INPP5B 抗体 (Middle Region) (ABIN2785875)

抗原

See all INPP5B 抗体
INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))

适用

人, 小鼠, 大鼠, 犬, 兔, 豚鼠, 马

宿主

  • 29
  • 2

克隆类型

  • 31
多克隆

标记

  • 15
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This INPP5B antibody is un-conjugated

应用范围

  • 18
  • 13
  • 12
  • 10
  • 5
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Middle Region

    序列

    IHNGQVPCHF EFINKPDEES YCKQWLNANP SRGFLLPDSD VEIDLELFVN

    预测反应

    Dog: 85%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 77%, Rat: 92%

    产品特性

    This is a rabbit polyclonal antibody against INPP5B. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human INPP5B
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 913 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tothova, Kollipara, Huntly, Lee, Castrillon, Cullen, McDowell, Lazo-Kallanian, Williams, Sears, Armstrong, Passegué, DePinho, Gilliland: "FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress." in: Cell, Vol. 128, Issue 2, pp. 325-39, (2007) (PubMed).

  • 抗原

    INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))

    别名

    INPP5B

    背景

    Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B is the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus.Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
    Alias Symbols: 5PTase, MGC65156, MGC71303
    Protein Interaction Partner: UBC, APP, SMURF1,
    Protein Size: 913

    分子量

    77 kDa

    基因ID

    3633

    NCBI登录号

    NM_005540, NP_005531

    UniProt

    P32019
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