INPP5B 抗体 (Middle Region)
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北京 101111
Quick Overview for INPP5B 抗体 (Middle Region) (ABIN2785875)
抗原
See all INPP5B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- IHNGQVPCHF EFINKPDEES YCKQWLNANP SRGFLLPDSD VEIDLELFVN
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预测反应
- Dog: 85%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 77%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against INPP5B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human INPP5B
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anti-Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) (AA 78-178) antibody
INPP5B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) antibodyINPP5B 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) (AA 1-748) antibodyINPP5B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) (C-Term) antibodyINPP5B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) (AA 950-979), (C-Term) antibodyINPP5B 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB27636 unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) (AA 957-987), (C-Term) antibodyINPP5B 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) (AA 1-748) antibodyINPP5B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) (AA 614-663) antibodyINPP5B 适用: 人, 犬, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 913 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress." in: Cell, Vol. 128, Issue 2, pp. 325-39, (2007) (PubMed).
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: "FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress." in: Cell, Vol. 128, Issue 2, pp. 325-39, (2007) (PubMed).
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- INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
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别名
- INPP5B
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背景
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Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B is the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus.Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: 5PTase, MGC65156, MGC71303
Protein Interaction Partner: UBC, APP, SMURF1,
Protein Size: 913 -
分子量
- 77 kDa
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基因ID
- 3633
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NCBI登录号
- NM_005540, NP_005531
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UniProt
- P32019
抗原
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