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Galectin 3 抗体 (N-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-Galectin 3 antibody is suitable to detect Galectin 3 in samples from 人, 小鼠, 大鼠, 兔, Pig, Cow, 犬, 豚鼠 和 马. It has been validated for WB 和 IHC.
产品编号 ABIN2785832
发货至: 中国
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Quick Overview for Galectin 3 抗体 (N-Term) (ABIN2785832)

抗原

See all Galectin 3 (LGALS3) 抗体
Galectin 3 (LGALS3)

适用

人, 小鼠, 大鼠, 兔, Pig, Cow, 犬, 豚鼠, 马

宿主

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兔

克隆类型

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  • 153
多克隆

标记

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This Galectin 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    原理

    LGALS3 Antibody - N-terminal region

    序列

    GASYPGAYPG QAPPGAYPGQ APPGAYPGAP GAYPGAPAPG VYPGPPSGPG

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against LGALS3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human LGALS3
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54688-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Guha, Bandyopadhyaya, Polumuri, Chumsri, Gade, Kalvakolanu, Ahmed et al.: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).

  • 抗原

    Galectin 3 (LGALS3)

    别名

    LGALS3

    背景

    Background Information: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.

    Gene Name: galectin 3

    Alternative Symbols: L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2

    Protein Name: galectin-3

    分子量

    26kDa

    基因ID

    3958

    NCBI登录号

    NP_002297

    UniProt

    P17931

    途径

    RTK signaling
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