KPNA3 抗体 (N-Term)
Quick Overview for KPNA3 抗体 (N-Term) (ABIN2785825)
抗原
See all KPNA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AENPSLENHR IKSFKNKGRD VETMRRHRNE VTVELRKNKR DEHLLKKRNV
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预测反应
- Cow: 77%, Dog: 77%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against KPNA3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human KPNA3
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anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (AA 1-210) antibody
KPNA3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (C-Term) antibodyKPNA3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (C-Term) antibodyVerified KPNA3 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (AA 3-220) antibodyKPNA3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (AA 422-521) antibodyKPNA3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (C-Term) antibody (Biotin)Verified KPNA3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 山羊 Polyclonal Biotin
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (N-Term) antibodyKPNA3 适用: 人, 小鼠, 大鼠, 豚鼠, 斑马鱼, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (C-Term) antibodyKPNA3 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 521 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))
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别名
- KPNA3
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背景
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The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3 is a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggest that karyopherin alpha-3 may be involved in the nuclear transport system.The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3, encodes a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggests that karyopherin alpha-3 may be involved in the nuclear transport system. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IPOA4, SRP1gamma, SRP4, hSRP1, SRP1
Protein Interaction Partner: TEX37, SLC5A11, APOL6, RPRD1A, ZCCHC10, MAT2B, NUP50, TSSC4, ZBTB24, DDX21, MTA1, HNRNPC, FTL, MVP, HSF1, UBC, MMS19, KPNA6, MCM6, MCM4, HDAC1, UL122, NACC1, NFE2L2, MYOD1, GTF2H1, GATA6, ERCC3, EPHA2, CBX5, TP53BP1, BARD1, ZNF131, COIL, CUL3, Ranbp2, Mki
Protein Size: 521 -
分子量
- 58 kDa
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基因ID
- 3839
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NCBI登录号
- NM_002267, NP_002258
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UniProt
- O00505
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途径
- Protein targeting to Nucleus
抗原
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