Granulin 抗体 (Middle Region)
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北京 101111
Quick Overview for Granulin 抗体 (Middle Region) (ABIN2785816)
抗原
See all Granulin (GRN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- CPMPNATCCS DHLHCCPQDT VCDLIQSKCL SKENATTDLL TKLPAHTVGD
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预测反应
- Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Rabbit: 85%
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产品特性
- This is a rabbit polyclonal antibody against GRN. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human GRN
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anti-Granulin (GRN) (AA 361-585) antibody
GRN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) (AA 31-269) antibodyGRN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) (Center) antibodyGRN 适用: 人, 小鼠, 大鼠 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) (AA 451-550) antibodyGRN 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) (AA 44-255) antibodyGRN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) (AA 494-593) antibodyGRN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Granulin (GRN) (AA 494-593) antibodyGRN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-Granulin (GRN) (AA 21-120) antibodyGRN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) (AA 20-310) antibodyGRN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) (Internal Region) antibodyVerified GRN 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Granulin (GRN)
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别名
- GRN
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背景
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Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.
Alias Symbols: CLN11, GEP, GP88, PCDGF, PEPI, PGRN
Protein Interaction Partner: OTX1, HOXA1, DLX2, SGTA, KRTAP26-1, KRTAP10-7, CCDC33, ARFGAP1, FANCL, NLK, GLRX3, EED, HECW2, Hk3, RPS6KA1, NPM1, POT1, FRAT1, YY1, TGM2, RAC1, PRKAB2, PIK3R2, SMAD9, KRT18, CRY1, CFTR, CCNG1, FBXO6, GFI1B, ATN1, CDK2, CRKL, VHL, SIRT3, ATXN7, CACNA1A, C
Protein Size: 438 -
分子量
- 48 kDa
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基因ID
- 2896
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NCBI登录号
- NM_002087, NP_002078
抗原
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