FCN1 抗体 (Middle Region)
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北京 101111
Quick Overview for FCN1 抗体 (Middle Region) (ABIN2785793)
抗原
See all FCN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- FCN1 Antibody - middle region
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序列
- GSQLGEFWLG NDNIHALTAQ GSSELRVDLV DFEGNHQFAK YKSFKVADEA
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预测反应
- Cow: 85%, Dog: 92%, Guinea Pig: 79%, Horse: 82%, Human: 100%, Mouse: 77%, Pig: 93%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against FCN1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FCN1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54605-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))
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别名
- FCN1
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背景
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Background Information: The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1(FCN1) is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity.The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Ficolin (collagen/fibrinogen domain containing) 1
Alternative Symbols: FCNM
Protein Name: Ficolin-1
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分子量
- 32kDa
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基因ID
- 2219
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NCBI登录号
- NP_001994
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UniProt
- O00602
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途径
- Complement System
抗原
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