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GLE1 抗体 (N-Term)

GLE1 适用: 人, 大鼠, 小鼠, 马, Cow, 犬, Pig, 兔, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785781
发货至: 中国
  • 抗原 See all GLE1 抗体
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    抗原表位
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 大鼠, 小鼠, 马, Cow, 犬, Pig, 兔, Saccharomyces cerevisiae, 斑马鱼
    宿主
    • 13
    • 3
    克隆类型
    • 15
    • 1
    多克隆
    标记
    • 12
    • 2
    • 1
    • 1
    This GLE1 antibody is un-conjugated
    应用范围
    • 11
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    LKLREAEQQR VKQAEQERLR KEEGQIRLRA LYALQEEMLQ LSQQLDASEQ
    预测反应
    Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 77%, Rat: 100%, Yeast: 90%, Zebrafish: 77%
    产品特性
    This is a rabbit polyclonal antibody against GLE1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human GLE1
    Top Product
    Discover our top product GLE1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 659 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    别名
    GLE1 (GLE1 产品)
    背景
    GLE1 is a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm.This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: GLE1L, hGLE1, LCCS, LCCS1
    Protein Interaction Partner: RNF2, UBC, ELAVL1, NUPL2, NUP155, EIF3F, UXT, KRT10,
    Protein Size: 659
    分子量
    75 kDa
    基因ID
    2733
    NCBI登录号
    NM_001499, NP_001490
    UniProt
    Q53GS7
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