GLE1 抗体 (N-Term)
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北京 101111
Quick Overview for GLE1 抗体 (N-Term) (ABIN2785781)
抗原
See all GLE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LKLREAEQQR VKQAEQERLR KEEGQIRLRA LYALQEEMLQ LSQQLDASEQ
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预测反应
- Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 77%, Rat: 100%, Yeast: 90%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against GLE1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GLE1
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anti-GLE1 RNA Export Mediator (GLE1) (AA 141-380) antibody
GLE1 适用: 人 ELISA, WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 140-240) antibodyGLE1 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 1-698) antibodyGLE1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 611-698) antibodyGLE1 适用: 大鼠 ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 218-267) antibodyGLE1 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (C-Term) antibodyGLE1 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 659 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GLE1 (GLE1 RNA Export Mediator (GLE1))
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别名
- GLE1
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背景
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GLE1 is a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm.This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: GLE1L, hGLE1, LCCS, LCCS1
Protein Interaction Partner: RNF2, UBC, ELAVL1, NUPL2, NUP155, EIF3F, UXT, KRT10,
Protein Size: 659 -
分子量
- 75 kDa
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基因ID
- 2733
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NCBI登录号
- NM_001499, NP_001490
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UniProt
- Q53GS7
抗原
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