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GFRA2 抗体 (C-Term)

This anti-GFRA2 antibody is a 兔 多克隆 antibody detecting GFRA2 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 马, Pig, Cow, 豚鼠 和 兔.
产品编号 ABIN2785779
发货至: 中国

Quick Overview for GFRA2 抗体 (C-Term) (ABIN2785779)

抗原

See all GFRA2 抗体
GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

适用

人, 小鼠, 大鼠, 犬, 马, Pig, Cow, 豚鼠, 兔

宿主

  • 54
  • 2
  • 1
  • 1

克隆类型

  • 56
  • 1
多克隆

标记

  • 29
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GFRA2 antibody is un-conjugated

应用范围

  • 48
  • 21
  • 13
  • 13
  • 10
  • 8
  • 7
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    NVSPKGPSFQ ATQAPRVEKT PSLPDDLSDS TSLGTSVITT CTSVQEQGLK

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against GFRA2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human GFRA2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 464 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

    别名

    GFRA2

    背景

    Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1.Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: GDNFRB, NRTNR-ALPHA, NTNRA, RETL2, TRNR2
    Protein Interaction Partner: PTEN, NRTN, GDNF,
    Protein Size: 464

    分子量

    47 kDa

    基因ID

    2675

    NCBI登录号

    NM_001495, NP_001486

    UniProt

    O00451
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