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Glutathione Reductase 抗体 (N-Term)

This anti-Glutathione Reductase antibody is a 兔 多克隆 antibody detecting Glutathione Reductase in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, 兔, 豚鼠, Cow, 犬 和 马. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2785662
发货至: 中国

Quick Overview for Glutathione Reductase 抗体 (N-Term) (ABIN2785662)

抗原

See all Glutathione Reductase (GSR) 抗体
Glutathione Reductase (GSR)

适用

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人, 大鼠, 小鼠, 兔, 豚鼠, Cow, 犬, 马

宿主

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克隆类型

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多克隆

标记

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This Glutathione Reductase antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    PTIEVSGKKY TAPHILIATG GMPSTPHESQ IPGASLGITS DGFFQLEELP

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against GSR. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human GSR
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 522 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hoffmann, Dietrich, Herrmann, Schacht, Albrecht, Methner: "Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 6093903, (2017) (PubMed).

  • 抗原

    Glutathione Reductase (GSR)

    别名

    GSR

    背景

    GSR belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. It maintains high levels of reduced glutathione in the cytosol. Both glutathione and glutathione reductase are inducible by D3T, and that upregulation of GSH biosynthesis underlies D3T-mediated cytoprotection against ROS/RNS-elicited injury to human vascular smooth muscle cells.
    Alias Symbols: MGC78522
    Protein Interaction Partner: SUMO1, CNDP2, GINS2, PROSC, AHSA1, NDRG1, DDX39A, NAMPT, KYNU, DDX39B, RPS6KA1, PEPD, MVD, LDHA, HSPD1, GBP2, EEF2, ADSS, C11orf49, UBC, FOLR1, ISG15, ELAVL1, SUMO4, PJA1, OCM, GSR,
    Protein Size: 522

    分子量

    56 kDa

    基因ID

    2936

    NCBI登录号

    NM_000637, NP_000628

    UniProt

    P00390

    途径

    Thyroid Hormone Synthesis, Cell RedoxHomeostasis
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