LIG1 抗体 (Middle Region)
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北京 101111
Quick Overview for LIG1 抗体 (Middle Region) (ABIN2785647)
抗原
See all LIG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- LIG1 Antibody - middle region
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序列
- PSVTSFILDT EAVAWDREKK QIQPFQVLTT RKRKEVDASE IQVQVCLYAF
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预测反应
- Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 85%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against LIG1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human LIG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54308-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
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别名
- LIG1
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背景
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Background Information: This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Gene Name: DNA ligase 1
Protein Name: DNA ligase 1
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分子量
- 102kDa
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基因ID
- 3978
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NCBI登录号
- NP_000225
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UniProt
- P18858
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途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
抗原
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