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PRKAA1 抗体 (N-Term)

The 兔多克隆 anti-PRKAA1 antibody is suitable to detect PRKAA1 in samples from 人, 大鼠和兔. It has been validated for WB 和 IHC.

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产品编号 ABIN2785614

发货至: 中国

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Quick Overview for PRKAA1 抗体 (N-Term) (ABIN2785614)

抗原

See all PRKAA1 抗体

PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

适用

人, 大鼠, 兔

宿主

兔

克隆类型

多克隆

标记

This PRKAA1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product PRKAA1 Primary Antibody

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N-Term

原理

PRKAA1 Antibody - N-terminal region

序列

GELFDYICKN GRKSDVPGVV KTGSTKELDE KESRRLFQQI LSGVDYCHRH

预测反应

Human: 100%, Rabbit: 85%, Rat: 85%

产品特性

This is a rabbit polyclonal antibody against PRKAA1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human PRKAA1
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 1-300) antibody
PRKAA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) antibody
PRKAA1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2B7 unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 28-257) antibody
PRKAA1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 351-450) antibody
PRKAA1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 351-450) antibody
PRKAA1 适用: 人 WB, IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) antibody
KD Validated PRKAA1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2685 unconjugated Recombinant Antibody

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 451-550) antibody
PRKAA1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D8 unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (pSer487) antibody
PRKAA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 325-543), (Catalytic Subunit) antibody
PRKAA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 451-550) antibody
PRKAA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D9 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8109326

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
抗原

PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

别名

PRKAA1

背景

Targeted Subunit: alpha-1
Background Information: PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Gene Name: Protein kinase, AMP-activated, alpha 1 catalytic subunit
Alternative Symbols: AMPK, AMPKa1, AMPK alpha 1
Protein Name: 5'-AMP-activated protein kinase catalytic subunit alpha-1

分子量

62kDa

基因ID

5562

NCBI登录号

NP_996790

UniProt

Q13131

途径

AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect