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PRKAA1 抗体 (N-Term)

This anti-PRKAA1 antibody is a 兔 多克隆 antibody detecting PRKAA1 in WB 和 IHC. Suitable for 人, 大鼠 和 兔.
产品编号 ABIN2785614
发货至: 中国
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Quick Overview for PRKAA1 抗体 (N-Term) (ABIN2785614)

抗原

See all PRKAA1 抗体
PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

适用

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人, 大鼠, 兔

宿主

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克隆类型

  • 153
  • 71
多克隆

标记

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This PRKAA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    GELFDYICKN GRKSDVPGVV KTGSTKELDE KESRRLFQQI LSGVDYCHRH

    预测反应

    Human: 100%, Rabbit: 85%, Rat: 85%

    产品特性

    This is a rabbit polyclonal antibody against PRKAA1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PRKAA1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 565 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

    别名

    PRKAA1

    背景

    PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
    Alias Symbols: AMPK, AMPKa1, MGC33776, MGC57364
    Protein Interaction Partner: PRKAG1, PRKAB2, PRKAB1, GOLGA2, PHC2, CTBP1, CDX4, AES, Trp53, INO80E, RFX6, TRIM27, KRT40, SSX2IP, PNMA5, UBXN11, RIMBP3, L3MBTL3, TSC22D4, VPS37B, HMBOX1, HOMEZ, THAP1, ROPN1, RAD54B, MTUS2, IKZF3, RBPMS, ABI2, ZBED1, BHLHE40, TRIP6, STK11, VPS52, PPARG
    Protein Size: 565

    分子量

    62 kDa

    基因ID

    5562

    NCBI登录号

    NM_206907, NP_996790

    UniProt

    Q13131

    途径

    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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