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- 抗原 See all APH1B (Aph1b) 抗体
- APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
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抗原表位
- N-Term
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适用
- 小鼠, 人, 大鼠, 兔, Cow, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APH1B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- IIDNKDGPTQ KYLLIFGAFV SVYIQEMFRF AYYKLLKKAS EGLKSINPGE
- 预测反应
- Cow: 92%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against APH1B. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human APH1B
- Top Product
- Discover our top product Aph1b Primary Antibody
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anti-Anterior Pharynx Defective 1 Homolog B (Aph1b) (AA 51-150) antibody
Aph1b 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog B (Aph1b) (AA 93-110) antibodyAph1b 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
- 别名
- APH1B (Aph1b 产品)
- 背景
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This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
Alias Symbols: APH-1B, PRO1328, PSFL, TAAV688
Protein Interaction Partner: UBC, PSENEN, NCSTN, PSEN2, PSEN1,
Protein Size: 257 - 分子量
- 28 kDa
- 基因ID
- 83464
- NCBI登录号
- NM_031301, NP_112591
- UniProt
- Q8WW43
- 途径
- Notch Signaling, Neurotrophin Signaling Pathway
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