APH1B 抗体 (N-Term)
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北京 101111
Quick Overview for APH1B 抗体 (N-Term) (ABIN2785589)
抗原
See all APH1B (Aph1b) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- APH1B Antibody - N-terminal region
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序列
- IIDNKDGPTQ KYLLIFGAFV SVYIQEMFRF AYYKLLKKAS EGLKSINPGE
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预测反应
- Cow: 92%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against APH1B. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human APH1B
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anti-Anterior Pharynx Defective 1 Homolog B (Aph1b) (AA 51-150) antibody
Aph1b 适用: 人 WB, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog B (Aph1b) (AA 93-110) antibodyAph1b 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53807-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
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别名
- APH1B
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背景
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Background Information: This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
Gene Name: anterior pharynx defective 1 homolog B (C. elegans)
Alternative Symbols: PSFL, APH-1B, PRO1328, TAAV688
Protein Name: Gamma-secretase subunit APH-1B
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分子量
- 28kDa
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基因ID
- 83464
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NCBI登录号
- NP_112591
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UniProt
- Q8WW43
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途径
- Notch Signaling, Neurotrophin Signaling Pathway
抗原
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