MLF1 抗体 (N-Term)
(1 reference)Quick Overview for MLF1 抗体 (N-Term) (ABIN2785560)
抗原
See all MLF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GRDLLSISDG RGRAHNRRGH NDGEDSLTHT DVSSFQTMDQ MVSNMRNYMQ
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预测反应
- Human: 100%, Mouse: 79%, Rabbit: 90%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against MLF1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MLF1
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anti-Myeloid Leukemia Factor 1 (MLF1) antibody
MLF1 适用: 人 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (AA 215-244), (C-Term) antibodyMLF1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18643 unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (AA 1-268) antibodyMLF1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) antibodyMLF1 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (AA 1-268) antibodyMLF1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (AA 1-268) antibodyMLF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (AA 1-268) antibodyMLF1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (Internal Region) antibodyMLF1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) antibodyMLF1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (AA 91-126) antibodyMLF1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51172 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 268 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Non-pathogenic protein aggregates in skeletal muscle in MLF1 transgenic mice." in: Journal of the neurological sciences, Vol. 264, Issue 1-2, pp. 77-86, (2007) (PubMed).
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: "Non-pathogenic protein aggregates in skeletal muscle in MLF1 transgenic mice." in: Journal of the neurological sciences, Vol. 264, Issue 1-2, pp. 77-86, (2007) (PubMed).
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- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
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别名
- MLF1
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背景
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MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. It interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. MLF1 suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest.It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Alias Symbols: -
Protein Interaction Partner: CENPU, COPS3, UBC, NRBP1, YWHAZ, GRIK5, MAGEA11,
Protein Size: 268 -
分子量
- 29 kDa
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基因ID
- 4291
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NCBI登录号
- NM_022443, NP_071888
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UniProt
- P58340
抗原
-
