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NUP98 抗体 (N-Term)

Name: NUP98 抗体 (N-Term)
SKU: ABIN2785490
Availability: OutOfStock

This anti-NUP98 antibody is a 兔多克隆 antibody detecting NUP98 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 马, 兔, Cow 和豚鼠.

WB Suggested Anti-NUP98 Antibody Titration: 0. (NUP98 抗体 (N-Term))

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产品编号 ABIN2785490

发货至: 中国

Quick Overview for NUP98 抗体 (N-Term) (ABIN2785490)

抗原

See all NUP98 抗体

NUP98 (Nucleoporin 98kDa (NUP98))

适用

人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This NUP98 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product NUP98 Primary Antibody

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N-Term

序列

EELRLEDYQA NRKGPQNQVG AGTTTGLFGS SPATSSATGL FSSSTTNSGF

预测反应

Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against NUP98. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human NUP98
anti-Nucleoporin 98kDa (NUP98) (AA 1-466) antibody
NUP98 适用: 人, 小鼠, 大鼠, Saccharomyces cerevisiae, Schizosaccharomyces pombe WB, ELISA, IF, ICC, DB 宿主: 大鼠 Monoclonal 2H10 unconjugated

anti-Nucleoporin 98kDa (NUP98) (GLFG Motif), (N-Term) antibody
NUP98 适用: 人, 小鼠, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena WB, IF 宿主: 小鼠 Monoclonal 21A10 unconjugated

anti-Nucleoporin 98kDa (NUP98) (FGxxN Motif), (N-Term) antibody
NUP98 适用: 人, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena WB, IF 宿主: 小鼠 Monoclonal 13C2 unconjugated

anti-Nucleoporin 98kDa (NUP98) (AA 965-1110) antibody
NUP98 适用: 人 WB, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Nucleoporin 98kDa (NUP98) antibody
NUP98 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Monoclonal 2H4 unconjugated Recombinant Antibody

anti-Nucleoporin 98kDa (NUP98) (AA 621-920) antibody
NUP98 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Nucleoporin 98kDa (NUP98) antibody
NUP98 适用: 人 WB, IP 宿主: 小鼠 Monoclonal unconjugated

anti-Nucleoporin 98kDa (NUP98) (AA 1-606) antibody
NUP98 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Nucleoporin 98kDa (NUP98) antibody
NUP98 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Nucleoporin 98kDa (NUP98) (AA 1-110) antibody
NUP98 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 937 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

NUP98 (Nucleoporin 98kDa (NUP98))

别名

NUP98

背景

The nuclear pore complex (NPC) is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kD nucleoporin is localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kD nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromsome translocatons in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kD nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kD precursor protein. This cleavage results in the 98 kD nucleoporin as well as a 96 kD nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kD nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromsome translocatons in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.
Alias Symbols: ADIR2, NUP196, NUP96
Protein Interaction Partner: UBC, SUMO2, SUMO3, CDC37, EED, CDC73, PAF1, ARFGEF2, FBXO6, NXF1, HDAC11, HDAC8, LMNA, HNRNPUL1, CSNK2A1, ECT2, NUP107, RAE1, SUMO1, NUMA1, rev, SIRT7, RAPGEF3, CTNNB1, NUP88, NUP159, NUP82, Nup98, Nup214, Nup188, tat, HDAC1, CREBBP, PTTG1, APC, NPM1, USP
Protein Size: 937

分子量

98 kDa

基因ID

4928

NCBI登录号

NM_005387, NP_005378

UniProt

A8KA17

途径

Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome