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ACRV1 抗体 (N-Term)

Cited in 1 publication. This 兔 多克隆 anti-ACRV1 antibody specifically detects ACRV1 in WB. The antibody is reactive with 人, 豚鼠 和 兔 samples.
产品编号 ABIN2785464
发货至: 中国
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Quick Overview for ACRV1 抗体 (N-Term) (ABIN2785464)

抗原

See all ACRV1 抗体
ACRV1 (Acrosomal Vesicle Protein 1 (ACRV1))

适用

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人, 豚鼠, 兔

宿主

  • 29
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克隆类型

  • 27
  • 22
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
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  • 1
This ACRV1 antibody is un-conjugated

应用范围

  • 35
  • 15
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  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 9
    • 2
    • 2
    N-Term

    序列

    MNRFLLLMSL YLLGSARGTS SQPNELSGSI DHQTSVQQLP GEFFSLENPS

    预测反应

    Guinea Pig: 79%, Human: 100%, Rabbit: 85%

    产品特性

    This is a rabbit polyclonal antibody against ACRV1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ACRV1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 265 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Reddi, Shore, Acharya, Herr: "Transcriptional regulation of spermiogenesis: insights from the study of the gene encoding the acrosomal protein SP-10." in: Journal of reproductive immunology, Vol. 53, Issue 1-2, pp. 25-36, (2001) (PubMed).

  • 抗原

    ACRV1 (Acrosomal Vesicle Protein 1 (ACRV1))

    别名

    ACRV1

    背景

    ACRV1 is a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans. This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72 % of the total acrosomal vesicle protein 1 messages, the second largest transcript comprises 15-32 %, the third and the fourth largest transcripts account for 3.4-8.3 % and 8.7-12.5 %, respectively, and the remaining transcripts combined account for < 1 % of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.
    Alias Symbols: D11S4365, SP-10, SPACA2
    Protein Size: 265

    分子量

    29 kDa

    基因ID

    56

    NCBI登录号

    NM_001612, NP_001603

    UniProt

    P26436
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