ACRV1 抗体 (N-Term)
Quick Overview for ACRV1 抗体 (N-Term) (ABIN2785464)
抗原
See all ACRV1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MNRFLLLMSL YLLGSARGTS SQPNELSGSI DHQTSVQQLP GEFFSLENPS
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预测反应
- Guinea Pig: 79%, Human: 100%, Rabbit: 85%
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产品特性
- This is a rabbit polyclonal antibody against ACRV1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACRV1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 265 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Transcriptional regulation of spermiogenesis: insights from the study of the gene encoding the acrosomal protein SP-10." in: Journal of reproductive immunology, Vol. 53, Issue 1-2, pp. 25-36, (2001) (PubMed).
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: "Transcriptional regulation of spermiogenesis: insights from the study of the gene encoding the acrosomal protein SP-10." in: Journal of reproductive immunology, Vol. 53, Issue 1-2, pp. 25-36, (2001) (PubMed).
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- ACRV1 (Acrosomal Vesicle Protein 1 (ACRV1))
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别名
- ACRV1
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背景
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ACRV1 is a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans. This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72 % of the total acrosomal vesicle protein 1 messages, the second largest transcript comprises 15-32 %, the third and the fourth largest transcripts account for 3.4-8.3 % and 8.7-12.5 %, respectively, and the remaining transcripts combined account for < 1 % of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.
Alias Symbols: D11S4365, SP-10, SPACA2
Protein Size: 265 -
分子量
- 29 kDa
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基因ID
- 56
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NCBI登录号
- NM_001612, NP_001603
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UniProt
- P26436
抗原
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