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AKR1C2 抗体 (N-Term)

The 兔 多克隆 anti-AKR1C2 antibody (ABIN2785423) specifically detects AKR1C2 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 马, 兔 和 Pig samples.
产品编号 ABIN2785423
发货至: 中国
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Quick Overview for AKR1C2 抗体 (N-Term) (ABIN2785423)

抗原

See all AKR1C2 抗体
AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

适用

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人, 小鼠, 大鼠, Cow, 马, 兔, Pig

宿主

  • 47
  • 17
兔

克隆类型

  • 50
  • 14
多克隆

标记

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This AKR1C2 antibody is un-conjugated

应用范围

  • 46
  • 29
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  • 10
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  • 7
  • 3
  • 2
  • 1
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  • 1
Western Blotting (WB)
  • 抗原表位

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    N-Term

    原理

    AKR1C2 Antibody - N-terminal region

    序列

    DGSVKREDIF YTSKLWSNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV

    预测反应

    Cow: 100%, Horse: 100%, Human: 100%, Mouse: 90%, Pig: 100%, Rabbit: 91%, Rat: 90%

    产品特性

    This is a rabbit polyclonal antibody against AKR1C2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1C2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53507-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

    别名

    AKR1C2

    背景

    Background Information: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

    Gene Name: Aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2, bile acid binding protein, 3-alpha hydroxysteroid dehydrogenase, type III)

    Alternative Symbols: DD, DD2, TDD, BABP, DD-2, DDH2, HBAB, HAKRD, MCDR2, SRXY8, DD/BABP, AKR1C-pseudo

    Protein Name: Aldo-keto reductase family 1 member C2

    分子量

    37kDa

    基因ID

    1646

    NCBI登录号

    NP_995317

    UniProt

    P52895

    途径

    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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