PDE12 抗体 (Middle Region)
Quick Overview for PDE12 抗体 (Middle Region) (ABIN2785355)
抗原
See all PDE12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- CLDYIFIDLN ALEVEQVIPL PSHEEVTTHQ ALPSVSHPSD HIALVCDLKW
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against 2'-PDE. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human 2'-PDE
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anti-Phosphodiesterase 12 (PDE12) (AA 17-300) antibody
PDE12 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 1-575) antibodyPDE12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (C-Term) antibodyPDE12 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬, 兔, 猴, Pig, Bat, 小鸡, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 290-602) antibodyPDE12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 362-390), (C-Term) antibodyPDE12 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB27765 unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 369-398), (C-Term) antibodyPDE12 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 609 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDE12 (Phosphodiesterase 12 (PDE12))
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别名
- PDE12
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背景
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2'-PDE is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. 2'-PDE also cleaves 3',5'-phosphodiester bond of oligoadenylates. 2'-PDE play a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.
Alias Symbols: 2'-PDE
Protein Interaction Partner: SUMO2, SUMO1, UBC, NEDD8, DCTPP1, NPLOC4, UBQLN2, EHD1, WDR4, PDLIM5, SAE1, UBA2, CUL5, XPNPEP1, STAT6, RAD23B, PGGT1B, DNAJB1, ADSL, APEX2, COPS5, CUL3, UBL4A,
Protein Size: 609 -
分子量
- 67 kDa
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基因ID
- 201626
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NCBI登录号
- NM_177966, NP_808881
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UniProt
- Q6L8Q7
抗原
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