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Klotho beta 抗体 (Middle Region)

KLB 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785343
发货至: 中国
  • 抗原 See all Klotho beta (KLB) 抗体
    Klotho beta (KLB)
    抗原表位
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔
    宿主
    • 22
    • 1
    克隆类型
    • 22
    • 1
    多克隆
    标记
    • 13
    • 7
    • 2
    • 1
    This Klotho beta antibody is un-conjugated
    应用范围
    • 18
    • 12
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    DAYTIRRGLF YVDFNSKQKE RKPKSSAHYY KQIIRENGFS LKESTPDVQG
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against KLB. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human KLB
    Top Product
    Discover our top product KLB Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1044 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Klotho beta (KLB)
    别名
    KLB (KLB 产品)
    别名
    KLB antibody, BKL antibody, AV071179 antibody, betaKlotho antibody, Klb-ps1 antibody, RGD1308227 antibody, klotho beta antibody, KLB antibody, Klb antibody
    背景
    KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.
    Alias Symbols: BKL, MGC142213
    Protein Interaction Partner: FGF21,
    Protein Size: 1044
    分子量
    120 kDa
    基因ID
    152831
    NCBI登录号
    NM_175737, NP_783864
    UniProt
    Q86Z14
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding
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