Klotho beta 抗体 (Middle Region)
Quick Overview for Klotho beta 抗体 (Middle Region) (ABIN2785343)
抗原
See all Klotho beta (KLB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- DAYTIRRGLF YVDFNSKQKE RKPKSSAHYY KQIIRENGFS LKESTPDVQG
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against KLB. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human KLB
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anti-Klotho beta (KLB) (AA 380-506) antibody
KLB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Klotho beta (KLB) (AA 846-965) antibodyKLB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Klotho beta (KLB) (AA 517-636) antibodyKLB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Klotho beta (KLB) (AA 1-130) antibodyKLB 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Klotho beta (KLB) (Middle Region) antibodyKLB 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Klotho beta (KLB) (AA 517-636) antibodyKLB 适用: 人 WB 宿主: 小鼠 Monoclonal 8# unconjugated
anti-Klotho beta (KLB) (AA 1-29) antibodyKLB 适用: 人 WB 宿主: 兔 Polyclonal RB55007 unconjugated
anti-Klotho beta (KLB) (AA 517-636) antibody (Biotin)KLB 适用: 人 WB 宿主: 兔 Polyclonal Biotin
anti-Klotho beta (KLB) (Internal Region) antibodyKLB 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1044 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Klotho beta (KLB)
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别名
- KLB
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背景
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KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.
Alias Symbols: BKL, MGC142213
Protein Interaction Partner: FGF21,
Protein Size: 1044 -
分子量
- 120 kDa
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基因ID
- 152831
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NCBI登录号
- NM_175737, NP_783864
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UniProt
- Q86Z14
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding
抗原
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