RDH12 抗体 (Middle Region)
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北京 101111
Quick Overview for RDH12 抗体 (Middle Region) (ABIN2785176)
抗原
See all RDH12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- RDH12 Antibody - middle region
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序列
- AKRLQGTGVT TYAVHPGVVR SELVRHSSLL CLLWRLFSPF VKTAREGAQT
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预测反应
- Cow: 85%, Dog: 92%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 85%, Rat: 79%, Yeast: 79%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against RDH12. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RDH12
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52973-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))
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别名
- RDH12
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背景
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Background Information: RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3). The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).
Gene Name: Retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
Alternative Symbols: RP53, LCA13, SDR7C2
Protein Name: Retinol dehydrogenase 12
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分子量
- 35kDa
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基因ID
- 145226
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NCBI登录号
- NP_689656
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UniProt
- Q96NR8
抗原
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