RDH12 抗体 (Middle Region)
(1 reference)Quick Overview for RDH12 抗体 (Middle Region) (ABIN2785175)
抗原
See all RDH12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- HIGKIPFHDL QSEKRYSRGF AYCHSKLANV LFTRELAKRL QGTGVTTYAV
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预测反应
- Dog: 93%, Human: 100%, Pig: 79%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against RDH12. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RDH12
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anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 1-316) antibody
RDH12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 217-316) antibodyRDH12 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 182-316) antibodyRDH12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 1-316) antibodyRDH12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 1-316) antibodyRDH12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 215-264) antibodyRDH12 适用: 人, Pig, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 179-228) antibodyRDH12 适用: 人, Pig, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) antibodyRDH12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 316 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Novel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: biochemical and clinical evaluations." in: Vision research, Vol. 47, Issue 15, pp. 2055-66, (2007) (PubMed).
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: "Novel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: biochemical and clinical evaluations." in: Vision research, Vol. 47, Issue 15, pp. 2055-66, (2007) (PubMed).
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- RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))
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别名
- RDH12
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背景
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RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).
Alias Symbols: FLJ30273, LCA3, LCA13, SDR7C2
Protein Interaction Partner: RBPMS, UBC, ANXA8L1, MAP1LC3A, BUB1,
Protein Size: 316 -
分子量
- 35 kDa
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基因ID
- 145226
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NCBI登录号
- NM_152443, NP_689656
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UniProt
- Q96NR8
抗原
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