METAP2 抗体 (N-Term)
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Quick Overview for METAP2 抗体 (N-Term) (ABIN2784850)
抗原
See all METAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ATGKKKKKKK KKRGPKVQTD PPSVPICDLY PNGVFPKGQE CEYPPTQDGR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against METAP2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human METAP2
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anti-Methionyl Aminopeptidase 2 (METAP2) (AA 2-212) antibody
METAP2 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) antibodyKD Validated METAP2 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB2565 unconjugated Recombinant Antibody
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 313-449) antibodyMETAP2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 1-478) antibodyMETAP2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) antibodyMETAP2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 95-144) antibodyMETAP2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 猴, Bat, Hamster, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 1-220) antibodyMETAP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) antibodyMETAP2 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 8F2 unconjugated Recombinant Antibody
anti-Methionyl Aminopeptidase 2 (METAP2) (C-Term) antibodyMETAP2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) antibodyMETAP2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 478 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- METAP2 (Methionyl Aminopeptidase 2 (METAP2))
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别名
- METAP2
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背景
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METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site.This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MAP2, MNPEP, p67, p67eIF2
Protein Interaction Partner: UBC, DAK, NPEPPS, GBP1, GAPDH, HMGA1, MTOR, EEF2K, APP, CALM1, S100A4, RAC1, MAPK3, EIF2S3, MAPK1, EIF2AK2, CDC42, E2F4,
Protein Size: 478 -
分子量
- 53 kDa
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基因ID
- 10988
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NCBI登录号
- NM_006838, NP_006829
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UniProt
- P50579
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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