DUSP8 抗体 (Middle Region)
Quick Overview for DUSP8 抗体 (Middle Region) (ABIN2784750)
抗原
See all DUSP8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- PAPPTPPATS ALQQGLRGLH LSSDRLQDTN RLKRSFSLDI KSAYAPSRRP
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against DUSP8. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human DUSP8
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anti-Dual Specificity Phosphatase 8 (DUSP8) antibody
DUSP8 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 8 (DUSP8) antibodyDUSP8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 8 (DUSP8) (N-Term) antibodyVerified DUSP8 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 8 (DUSP8) (AA 359-408) antibodyDUSP8 适用: 人, 小鼠, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 8 (DUSP8) (Middle Region) antibodyDUSP8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 8 (DUSP8) (AA 456-487), (C-Term) antibodyDUSP8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5874 unconjugated
anti-Dual Specificity Phosphatase 8 (DUSP8) (C-Term) antibodyDUSP8 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 625 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))
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别名
- DUSP8
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背景
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DUSP8 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP8inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.
Alias Symbols: C11orf81, FLJ42476, FLJ42958, HB5, HVH-5, HVH8
Protein Interaction Partner: MAPK9, MAPK8, CDC25A,
Protein Size: 625 -
分子量
- 66 kDa
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基因ID
- 1850
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NCBI登录号
- NM_004420, NP_004411
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UniProt
- Q13202
抗原
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